Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL974062 | 1.00 | LMNA (0.54) | LMNAMAPK1GABRA1GABRB2TSHR | |
| SCHEMBL11349953 | 1.00 | LMNA (0.54) | LMNAMAPK1GABRA1GABRB2TSHR | |
| SCHEMBL31107080 | 1.00 | LMNA (0.54) | LMNAMAPK1GABRA1GABRB2TSHR | |
| SCHEMBL7522933 | 0.98 | LMNA (0.52) | LMNAMAPK1GABRA1GABRB2TSHR | |
| Hydrochloric Acid SCHEMBL1375900 | 0.98 | LMNA (0.52) | LMNAMAPK1GABRA1GABRB2TSHR | |
| SCHEMBL7522050 | 0.98 | LMNA (0.52) | LMNAMAPK1GABRA1GABRB2TSHR | |
| Ammonia Solution, Strong SCHEMBL7523599 | 0.98 | LMNA (0.52) | LMNAMAPK1GABRA1GABRB2TSHR | |
| SCHEMBL7522924 | 0.98 | LMNA (0.52) | LMNAMAPK1GABRA1GABRB2TSHR | |
| Water SCHEMBL7529368 | 0.98 | LMNA (0.52) | LMNAMAPK1GABRA1GABRB2TSHR | |
| SCHEMBL7522058 | 0.98 | LMNA (0.52) | LMNAMAPK1GABRA1GABRB2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109467502-B | Method for splitting mandelic acid compound enantiomer | 湖南科技大学 | 2021-07-30 | — | — | CN | claimed |
| CN-109467502-A | A method of splitting almond acid compounds enantiomer | 湖南科技大学 | 2019-03-15 | — | — | CN | claimed |
| US-6359172-B1 | Method of preparing 2- and 4-hydroxymandelic acid | GERARD KESSELS SOCIEDAD ANONIMA, S.A. (ES) | 2002-03-19 | — | — | US | claimed |
| EP-0987245-B1 | A method of preparing 2- and 4-hydroxymandelic acid | GERARD KESSELS S A (ES) | 2002-03-13 | — | — | EP | claimed |
| EP-0987245-A1 | A method of preparing 2- and 4-hydroxymandelic acid | Gerard Kessels S.A. (ES) | 2000-03-22 | — | — | EP | claimed |
| EP-0536960-B1 | Preparation of 2-hydroxymandelic acids and 2-hydroxybenzaldehydes | ZENECA LTD (GB) | 1996-09-11 | — | — | EP | claimed |
| US-5248816-A | From glycolic acid and borate | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-09-28 | — | — | US | claimed |
| EP-0536960-A2 | Preparation of 2-hydroxymandelic acids and 2-hydroxybenzaldehydes | ZENECA LIMITED (GB) | 1993-04-14 | — | — | EP | claimed |
| JP-5201917-A | — | — | None | — | — | JP | disclosed |
| WO-2025243298-A1 | NOVEL SUBSTITUTED AMINOCYCLOHEXANECARBONITRILES | ADAMA MAKHTESHIM LTD. (IL) | 2025-11-27 | — | — | WO | disclosed |
| US-20230416182-A1 | PROCESS FOR PREPARING FRAMBIONE | RHODIA OPERATIONS (FR) | 2023-12-28 | — | — | US | disclosed |
| CN-108047033-B | Reaction device and method for preparing mandelic acid compound | 江西科苑生物药业有限公司 | 2023-12-01 | — | — | CN | disclosed |
| EP-4255879-A1 | METHOD FOR PRODUCING FRAMBINONE | RHODIA OPERATIONS (FR) | 2023-10-11 | — | — | EP | disclosed |
| EP-3589636-B1 | PROCESSES FOR PREPARING ACC INHIBITORS AND SOLID FORMS THEREOF | GILEAD SCIENCES INC (US) | 2023-09-13 | — | — | EP | disclosed |
| JP-H05201917-A | PRODUCTION OF 2-HYDROXY MANDELIC ACID | IMPERIAL CHEM IND PLC <ICI> | 1993-08-10 | — | — | JP | disclosed |
| EP-0536960-A2 | Preparation of 2-hydroxymandelic acids and 2-hydroxybenzaldehydes | ZENECA LIMITED (GB) | 1993-04-14 | — | — | EP | disclosed |
| EP-0536960-A2 | Preparation of 2-hydroxymandelic acids and 2-hydroxybenzaldehydes | ZENECA LIMITED (GB) | 1993-04-14 | — | — | EP | disclosed |
| EP-0536960-A2 | Preparation of 2-hydroxymandelic acids and 2-hydroxybenzaldehydes | ZENECA LIMITED (GB) | 1993-04-14 | — | — | EP | disclosed |
| US-4978784-A | Process for industrial manufacture of sodium parahydroxymandelate | SOCIETE FRANCAISE HOECHST (FR) | 1990-12-18 | — | — | US | disclosed |
| US-4385006-A | Process for preparing aromatic nitriles | 501 SOCIETE FRANCAISE HOECHST (FR) | 1983-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416182-A1 | PROCESS FOR PREPARING FRAMBIONE | GRHPR, FDPS, FPGS | LMNA 652/4885MAPK1 3956/4885GABRA1 3770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.