Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 13/20 | 0.45 |
| ▸ | PPARA | Q07869 | 11/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740628 | 1.00 | ACE (0.49) | ACESRRPKMKMT2APPARG | |
| SCHEMBL9354983 | 0.92 | ACE (0.47) | ACESRRPKMPPARGPPARA | |
| SCHEMBL9354973 | 0.92 | ACE (0.47) | ACESRRPKMPPARGPPARA | |
| SCHEMBL8682156 | 0.86 | SRR (0.51) | ACESRRKMT2APPARGPPARA | |
| SCHEMBL8909660 | 0.86 | SRR (0.51) | ACESRRKMT2APPARGPPARA | |
| SCHEMBL9359097 | 0.86 | SRR (0.51) | ACESRRKMT2APPARGPPARA | |
| SCHEMBL9358262 | 0.84 | ACE (0.45) | ACESRRPKMPPARGPPARA | |
| SCHEMBL9358267 | 0.84 | ACE (0.45) | ACESRRPKMPPARGPPARA | |
| SCHEMBL7278049 | 0.83 | HSD17B10 (0.58) | ACESRRPPARGPPARA | |
| SCHEMBL9359129 | 0.83 | DPP4 (0.49) | ACESRRPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104869-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-04-14 | — | — | US | disclosed |