Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.33 |
| ▸ | TUBB | P07437 | 4/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.33 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.33 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1969418 | 0.81 | KDM4E (0.34) | MAPTKDM4E | |
| SCHEMBL1539241 | 0.76 | CA1 (0.39) | MAPTTDP1CA1CA2CA4 | |
| SCHEMBL9740698 | 0.71 | KDM4E (0.37) | MAPTTDP1CA1CA2CA4 | |
| SCHEMBL9741890 | 0.70 | CYP19A1 (0.38) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL9739018 | 0.69 | TUBB4A (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30701949 | 0.67 | CA9 (0.50) | MAPTTDP1CA1CA2CA4 | |
| SCHEMBL3674074 | 0.67 | CA9 (0.50) | MAPTTDP1CA1CA2CA4 | |
| SCHEMBL2085433 | 0.65 | TUBB4A (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL38660362 | 0.65 | TUBB4A (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9739550 | 0.64 | CYP19A1 (0.36) | MAPTTDP1CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |