Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 2/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.41 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741670 | 0.90 | KDM4E (0.58) | ALDH1A1KDM4EFFAR1LPAR3CYP2C9 | |
| SCHEMBL9157220 | 0.89 | ALDH1A1 (0.51) | ALDH1A1TSHRKDM4EFFAR1LPAR3 | |
| SCHEMBL9742737 | 0.88 | ALDH1A1 (0.58) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9741238 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KDM4ELPAR3CYP2C9CYP2C19 | |
| SCHEMBL9742526 | 0.83 | MEN1 (0.47) | ALDH1A1TSHRKDM4ELPAR3CYP2C9 | |
| SCHEMBL10356228 | 0.82 | NPY5R (0.52) | ALDH1A1KDM4EFFAR1LPAR3CYP2C9 | |
| SCHEMBL9742730 | 0.81 | ESR1 (0.42) | ALDH1A1TSHRMEN1KMT2ALMNA | |
| SCHEMBL9742180 | 0.80 | PGR (0.46) | ALDH1A1KDM4EFFAR1LPAR3CYP2C9 | |
| SCHEMBL30334516 | 0.79 | ALDH1A1 (0.54) | ALDH1A1TSHRKDM4ELPAR3CYP2C9 | |
| SCHEMBL26215299 | 0.79 | ALDH1A1 (0.54) | ALDH1A1TSHRKDM4ELPAR3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110983-A | Intermediates for heat-resistant polyamides and polyimides | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-05 | — | — | US | disclosed |
| EP-0389961-A1 | Monomerides containing the hexafluoroisopropyl group, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-03 | — | — | EP | disclosed |