Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.57 |
| ▸ | TUBB | P07437 | 4/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.57 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.57 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.57 |
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742331 | 0.91 | TUBB1 (0.58) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9740244 | 0.81 | MAPT (0.58) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9741988 | 0.80 | TUBB4A (0.52) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9740914 | 0.75 | TUBB1 (0.56) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9740778 | 0.75 | ALOX5 (0.36) | MAOB | |
| SCHEMBL533492 | 0.75 | MEN1 (0.53) | KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9738939 | 0.75 | GAK (0.43) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL24087695 | 0.74 | TUBB1 (0.69) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9740472 | 0.74 | GAA (0.59) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6955320 | 0.74 | HPGD (0.53) | KDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |