Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 10/20 | 0.33 |
| ▸ | MAOA | P21397 | 5/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740451 | 0.78 | INSR (0.34) | — | |
| SCHEMBL9740911 | 0.75 | TUBB1 (0.57) | MAOB | |
| SCHEMBL9740797 | 0.75 | MAOB (0.33) | MAOBMAOARHEBCA12CA1 | |
| SCHEMBL9740598 | 0.74 | CYP2D6 (0.39) | ALOX5MAOBMAOAF2 | |
| SCHEMBL6955320 | 0.71 | HPGD (0.53) | CA12CA1CA7CA9 | |
| SCHEMBL694423 | 0.68 | ALOX5 (0.62) | ALOX5MAOBMAOA | |
| SCHEMBL533492 | 0.66 | MEN1 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5257014 | 0.64 | DRD3 (0.54) | — | |
| SCHEMBL20481932 | 0.63 | MEN1 (0.45) | MAOAF2ACHE | |
| SCHEMBL207534 | 0.63 | AHR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |