Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739995 | 0.98 | NMT1 (0.34) | NMT1ALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL12856118 | 0.80 | CA1 (0.37) | ALDH1A1KDM4EMAPT | |
| SCHEMBL345129 | 0.80 | CA1 (0.37) | ALDH1A1KDM4EMAPT | |
| SCHEMBL1023387 | 0.78 | CA1 (0.35) | ALDH1A1KDM4EMAPT | |
| SCHEMBL1024671 | 0.78 | CA1 (0.35) | ALDH1A1KDM4EMAPT | |
| SCHEMBL1022571 | 0.78 | CA1 (0.35) | ALDH1A1KDM4EMAPT | |
| SCHEMBL1022384 | 0.78 | CA1 (0.35) | ALDH1A1KDM4EMAPT | |
| SCHEMBL9520705 | 0.76 | PDE10A (0.38) | ALDH1A1KDM4EMEN1CYP1A2KMT2A | |
| SCHEMBL16404373 | 0.74 | POLB (0.43) | ALDH1A1HPGD | |
| SCHEMBL9739990 | 0.74 | NMT1 (0.54) | NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153227-A | Treatment of diabetes and galactosemia complications | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-06 | — | — | US | disclosed |