SCHEMBL345129

SCHEMBL345129

Cc1cc(C)c(S(=O)O)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
MMP8 P22894 1/20 0.37
MMP13 P45452 1/20 0.37
RAPGEF4 Q8WZA2 2/20 0.36
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 2/20 0.36
LMNA P02545 2/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
TP53 P04637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TPMT P51580 1/20 0.33
F2 P00734 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12856118 1.00 CA1 (0.37) CA1CA2MMP1MMP2MMP9
SCHEMBL1023387 0.97 CA1 (0.35) CA1CA2MMP1MMP2MMP9
SCHEMBL1024671 0.97 CA1 (0.35) CA1CA2MMP1MMP2MMP9
SCHEMBL1022384 0.97 CA1 (0.35) CA1CA2MMP1MMP2MMP9
SCHEMBL1022571 0.97 CA1 (0.35) CA1CA2MMP1MMP2MMP9
SCHEMBL9520705 0.80 PDE10A (0.38) ALDH1A1KDM4EMAPTTDP1
SCHEMBL9740926 0.80 NMT1 (0.35) ALDH1A1KDM4EMAPT
SCHEMBL9739995 0.78 NMT1 (0.34) ALDH1A1KDM4E
SCHEMBL16404373 0.78 POLB (0.43) ALDH1A1LMNATDP1HSD17B10
SCHEMBL6730284 0.75 PGK1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 491 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117142916-B Preparation method of allyl sulfone compound 安徽金桐精细化学有限公司 2024-10-11 CN claimed
CN-117142916-A Preparation method of allyl sulfone compound 安徽金桐精细化学有限公司 2023-12-01 CN claimed
EP-2110392-B1 DIVIDED REDOX-CURING-TYPE COMPOSITION KURARAY NORITAKE DENTAL INC (JP) 2020-05-06 EP claimed
US-8329845-B2 Divided redox-curing type composition KURARAY NORITAKE DENTAL INC. (JP) 2012-12-11 US claimed
US-6984673-B2 Dental cement composition KURARAY CO., LTD. (JP) 2006-01-10 US claimed
US-20260144714-A1 KIT FOR PREPARING CURABLE COMPOSITION FOR DENTAL MATERIAL, CURABLE COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2026-05-28 US disclosed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
EP-4725470-A1 CURABLE DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-04-15 EP disclosed
EP-3733152-B1 POWDER-LIQUID TYPE RESIN-REINFORCED DENTAL GLASS IONOMER CEMENT COMPOSITION SHOFU INC (JP) 2026-03-11 EP disclosed
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT SHOFU INC. (JP) 2026-03-05 US disclosed
EP-4659729-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION Shofu Inc. (JP) 2025-12-10 EP disclosed
US-12478562-B2 Dental restoration material composition KURARAY NORITAKE DENTAL INC. (JP) 2025-11-25 US disclosed
US-6191191-B1 USED AS BONDING AGENT, COMPOSITE RESIN, ADHESIVE AGENT, PRIMER AND OPAQUE PRIMER FOR DENTAL USE; LIGHT RESISTANCE; ADHESION TO TOOTH SURFACE AND METALS; COLORFASTNESS KURARAY CO., LTD. (JP) 2001-02-20 US disclosed
CN-1277834-A Cementation composite and prepn. method therefor KURARAY CO (JP) 2000-12-27 CN disclosed
EP-1057468-A1 Adhesive composition and method for producing it KURARAY CO., LTD. (JP) 2000-12-06 EP disclosed
CN-1273809-A Binding compsns. KURARAY CO (JP) 2000-11-22 CN disclosed
EP-1051961-A1 Bonding compositions for dental use KURARAY CO., LTD. (JP) 2000-11-15 EP disclosed
CN-1253767-A Adhesive compound for tooth KURARAY CO (JP) 2000-05-24 CN disclosed
EP-0980682-A1 Bonding compositions for dental use KURARAY CO., LTD. (JP) 2000-02-23 EP disclosed
EP-0948955-A1 POLYMERIZABLE DENTAL COMPOSITION KURARAY CO., LTD. (JP) 1999-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT BOLA2; BOLA2B, LBR, COL2A1 CA1 1024/4885CA2 959/4885MMP1 1019/4885
US-20260144714-A1 KIT FOR PREPARING CURABLE COMPOSITION FOR DENTAL MATERIAL, CURABLE COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL CAD, KIT, ILK CA1 291/4885CA2 1517/4885MMP1 1872/4885
US-12478562-B2 Dental restoration material composition CAD, MAT2B, RER1 CA1 1287/4885CA2 2513/4885MMP1 3906/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL CA1 166/4885CA2 473/4885MMP1 1950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.