Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL345129 | 0.80 | CA1 (0.37) | ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL12856118 | 0.80 | CA1 (0.37) | ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL1022571 | 0.78 | CA1 (0.35) | ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL1022384 | 0.78 | CA1 (0.35) | ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL1023387 | 0.78 | CA1 (0.35) | ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL1024671 | 0.78 | CA1 (0.35) | ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL9740926 | 0.76 | NMT1 (0.35) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL9739995 | 0.74 | NMT1 (0.34) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL16404373 | 0.74 | POLB (0.43) | ALDH1A1TSHRTDP1CYP2C19 | |
| SCHEMBL6730284 | 0.71 | PGK1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0408713-B1 | PHENYLSULPHONE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-19 | — | — | EP | claimed |
| EP-0408713-A1 | PHENYLSULPHONE DERIVATIVES. | ICI PLC (GB) | 1991-01-23 | — | — | EP | claimed |
| WO-1990008761-A1 | PHENYLSULPHONE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-08-09 | — | — | WO | claimed |
| EP-0408713-B1 | PHENYLSULPHONE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-19 | — | — | EP | disclosed |
| EP-0408713-A1 | PHENYLSULPHONE DERIVATIVES. | ICI PLC (GB) | 1991-01-23 | — | — | EP | disclosed |
| WO-1990008761-A1 | PHENYLSULPHONE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-08-09 | — | — | WO | disclosed |