SCHEMBL1023387

SCHEMBL1023387

Cc1cc(C)c(S(=O)O)c(C)c1.[NaH]

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
MMP1 P03956 1/20 0.35
MMP2 P08253 1/20 0.35
MMP9 P14780 1/20 0.35
MMP8 P22894 1/20 0.35
MMP13 P45452 1/20 0.35
RAPGEF4 Q8WZA2 2/20 0.35
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 2/20 0.34
LMNA P02545 2/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32
TP53 P04637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TPMT P51580 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL345129 0.97 CA1 (0.37) CA1CA2MMP1MMP2MMP9
SCHEMBL12856118 0.97 CA1 (0.37) CA1CA2MMP1MMP2MMP9
SCHEMBL1024671 0.95 CA1 (0.35) CA1CA2MMP1MMP2MMP9
SCHEMBL1022571 0.95 CA1 (0.35) CA1CA2MMP1MMP2MMP9
SCHEMBL1022384 0.95 CA1 (0.35) CA1CA2MMP1MMP2MMP9
SCHEMBL9739995 0.81 NMT1 (0.34) ALDH1A1KDM4E
SCHEMBL9520705 0.78 PDE10A (0.38) ALDH1A1KDM4EMAPTTDP1
SCHEMBL9740926 0.78 NMT1 (0.35) ALDH1A1KDM4EMAPT
SCHEMBL16404373 0.76 POLB (0.43) ALDH1A1LMNATDP1HSD17B10
SCHEMBL6730284 0.73 PGK1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4239004-A None JP disclosed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
US-12478562-B2 Dental restoration material composition KURARAY NORITAKE DENTAL INC. (JP) 2025-11-25 US disclosed
US-12465559-B2 Fluorescent curable dental composition and cured product thereof KURARAY NORITAKE DENTAL INC. (JP) 2025-11-11 US disclosed
EP-4613256-A1 DENTAL ADHESIVE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2025-09-10 EP disclosed
US-20250213434-A1 DENTAL CURABLE COMPOSITION HAVING FAVORABLE COLOR COMPATIBILITY KURARAY NORITAKE DENTAL INC. (JP) 2025-07-03 US disclosed
WO-2025126917-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2025-06-19 WO disclosed
US-20250082550-A1 BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS DENTSPLY SIRONA INC. (US) 2025-03-13 US disclosed
US-20250064687-A1 DENTAL CURABLE COMPOSITION AND DENTAL PROSTHESIS COMPRISING BASE MATERIAL AND RESIN LAYER KURARAY NORITAKE DENTAL INC. (JP) 2025-02-27 US disclosed
US-20250057732-A1 DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2025-02-20 US disclosed
US-6355704-B1 BACTERICIDE PRIMERS; BONDING TO TEETH KURARAY CO., LTD. (JP) 2002-03-12 US disclosed
US-20020016417-A1 Fitting composition, body-worn tool produced using the same, and method for producing the same KURARAY CO., LTD (JP) 2002-02-07 US disclosed
EP-1167408-A1 Fitting composition, body-worn tool produced using the same, and method for producing the same Kuraray Co., Ltd. (JP) 2002-01-02 EP disclosed
EP-1057468-A1 Adhesive composition and method for producing it KURARAY CO., LTD. (JP) 2000-12-06 EP disclosed
EP-1051961-A1 Bonding compositions for dental use KURARAY CO., LTD. (JP) 2000-11-15 EP disclosed
EP-0980682-A1 Bonding compositions for dental use KURARAY CO., LTD. (JP) 2000-02-23 EP disclosed
US-5486544-A AROMATIC SULFINATE POLYMERIZATION CATALYST KURARAY CO., LTD. (JP) 1996-01-23 US disclosed
EP-0408357-B1 Polymerizable composition KURARAY CO (JP) 1994-06-01 EP disclosed
JP-H04239004-A POLYMERIZABLE COMPOSITION KURARAY CO LTD 1992-08-26 JP disclosed
EP-0408357-A2 Polymerizable composition KURARAY CO., LTD. (JP) 1991-01-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12465559-B2 Fluorescent curable dental composition and cured product thereof BRD1, TBCA, BAZ1A CA1 3244/4885CA2 3451/4885MMP1 912/4885
US-20250064687-A1 DENTAL CURABLE COMPOSITION AND DENTAL PROSTHESIS COMPRISING BASE MATERIAL AND RESIN LAYER MGMT, SEM1, CARM1 CA1 192/4885CA2 2303/4885MMP1 2640/4885
US-12478562-B2 Dental restoration material composition CAD, MAT2B, RER1 CA1 1287/4885CA2 2513/4885MMP1 3906/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL CA1 166/4885CA2 473/4885MMP1 1950/4885
US-20250057732-A1 DENTAL CURABLE COMPOSITION CAD, MMAB, DNMT3L CA1 929/4885CA2 2758/4885MMP1 3707/4885
US-20250082550-A1 BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS DUOX2, DUOX1, QSOX1 CA1 601/4885CA2 632/4885MMP1 2922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.