Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741280 | 1.00 | LMNA (0.49) | LMNATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL112399 | 0.84 | LMNA (0.55) | LMNATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL10408835 | 0.82 | LMNA (0.53) | LMNATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL8343471 | 0.77 | LMNA (0.50) | LMNATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL21447183 | 0.76 | HCAR2 (0.51) | TSHRALDH1A1HSD17B10HCAR2OPRM1 | |
| Salicylic Acid SCHEMBL9741275 | 0.75 | ALDH1A1 (0.55) | LMNATSHRALDH1A1KDM4EHPGD | |
| Salicylic Acid SCHEMBL9740960 | 0.75 | ALDH1A1 (0.55) | LMNATSHRALDH1A1KDM4EHPGD | |
| Salicylic Acid SCHEMBL9740951 | 0.75 | ALDH1A1 (0.55) | LMNATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL27908807 | 0.74 | TSHR (0.63) | LMNATSHRALDH1A1KDM4EHPGD | |
| SCHEMBL10592352 | 0.74 | HCAR2 (0.53) | ALDH1A1KDM4EHSD17B10HCAR2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081117-A | Treatment of memory dysfunctions such as in Alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-01-14 | — | — | US | claimed |