Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740998 | 1.00 | REN (0.43) | RENMMP2MMP9MMP8TSHR | |
| SCHEMBL9740310 | 0.79 | REN (0.41) | RENMMP2MMP9MMP8 | |
| SCHEMBL9740313 | 0.79 | REN (0.41) | RENMMP2MMP9MMP8 | |
| SCHEMBL9742942 | 0.78 | REN (0.54) | REN | |
| SCHEMBL9742947 | 0.78 | REN (0.54) | REN | |
| SCHEMBL9740882 | 0.74 | MMP2 (0.54) | RENMMP2MMP9MMP8 | |
| SCHEMBL9740887 | 0.74 | MMP2 (0.54) | RENMMP2MMP9MMP8 | |
| SCHEMBL9740075 | 0.74 | REN (0.48) | REN | |
| SCHEMBL9740080 | 0.74 | REN (0.48) | REN | |
| SCHEMBL10421591 | 0.72 | REN (0.56) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104869-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-04-14 | — | — | US | claimed |