Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | MMP9 | P14780 | 2/20 | 0.54 |
| ▸ | MMP8 | P22894 | 2/20 | 0.54 |
| ▸ | REN | P00797 | 15/20 | 0.50 |
| ▸ | IDE | P14735 | 1/20 | 0.43 |
| ▸ | IL1RN | P18510 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740882 | 1.00 | MMP2 (0.54) | MMP2MMP9MMP8RENIDE | |
| SCHEMBL9739605 | 0.81 | MMP2 (0.51) | MMP2MMP9MMP8RENIDE | |
| SCHEMBL9739604 | 0.81 | MMP2 (0.51) | MMP2MMP9MMP8RENIDE | |
| SCHEMBL9741586 | 0.78 | MMP2 (0.51) | MMP2MMP9MMP8RENIDE | |
| SCHEMBL9741583 | 0.78 | MMP2 (0.51) | MMP2MMP9MMP8RENIDE | |
| SCHEMBL9740864 | 0.75 | MMP2 (0.55) | MMP2MMP9MMP8REN | |
| SCHEMBL9740857 | 0.75 | MMP2 (0.55) | MMP2MMP9MMP8REN | |
| SCHEMBL9740998 | 0.74 | REN (0.43) | MMP2MMP9MMP8REN | |
| SCHEMBL9740996 | 0.74 | REN (0.43) | MMP2MMP9MMP8REN | |
| SCHEMBL9741102 | 0.74 | MMP2 (0.57) | MMP2MMP9MMP8RENIL1RN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104869-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-04-14 | — | — | US | claimed |