Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | SELE | P16581 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426904 | 0.85 | HSD17B10 (0.50) | HSD17B10ALDH1A1HTTTDP1SMN1; SMN2 | |
| SCHEMBL9741411 | 0.83 | ICAM1 (0.43) | ICAM1SELEVCAM1HSD17B10ALDH1A1 | |
| SCHEMBL9741908 | 0.79 | NR2E3 (0.46) | ICAM1SELEVCAM1HSD17B10ALDH1A1 | |
| SCHEMBL9741437 | 0.78 | NR2E3 (0.45) | ICAM1SELEVCAM1HSD17B10ALDH1A1 | |
| SCHEMBL9741863 | 0.74 | NPSR1 (0.39) | ICAM1SELEVCAM1HSD17B10ALDH1A1 | |
| SCHEMBL857100 | 0.73 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2LMNAHPGDTP53 | |
| SCHEMBL9427014 | 0.72 | HSD17B10 (0.50) | HSD17B10ALDH1A1HTTTDP1SMN1; SMN2 | |
| SCHEMBL9740941 | 0.71 | NPSR1 (0.41) | HSD17B10ALDH1A1HTTTDP1SMN1; SMN2 | |
| SCHEMBL9427382 | 0.70 | NR2E3 (0.48) | ICAM1SELEVCAM1HSD17B10ALDH1A1 | |
| SCHEMBL31120582 | 0.69 | POLB (0.47) | HSD17B10ALDH1A1TDP1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006965-A1 | HERBICIDAL SULFONYLUREA DERIVATIVES | ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) | 1992-04-30 | — | — | WO | disclosed |