Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | CDC7 | O00311 | 2/20 | 0.44 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741411 | 0.87 | ICAM1 (0.43) | HSD17B10ALDH1A1TDP1HTTPKM | |
| SCHEMBL9427276 | 0.83 | NR2E3 (0.43) | HSD17B10ALDH1A1TDP1HTTPKM | |
| SCHEMBL9426904 | 0.77 | HSD17B10 (0.50) | HSD17B10ALDH1A1TDP1HTTPKM | |
| SCHEMBL367099 | 0.76 | POLB (0.56) | HSD17B10TDP1PKMMAPTL3MBTL1 | |
| SCHEMBL30953885 | 0.73 | HSD17B10 (0.46) | HSD17B10ALDH1A1TDP1HTTPKM | |
| SCHEMBL3257038 | 0.72 | LMNA (0.71) | ALDH1A1PKMCDC7DBF4MAPT | |
| SCHEMBL3257036 | 0.72 | LMNA (0.56) | ALDH1A1HTTPKMCDC7DBF4 | |
| SCHEMBL9741013 | 0.72 | ICAM1 (0.42) | HSD17B10ALDH1A1TDP1HTTPKM | |
| SCHEMBL9427382 | 0.72 | NR2E3 (0.48) | HSD17B10ALDH1A1TDP1HTTPKM | |
| SCHEMBL5477397 | 0.69 | CALM1 (0.46) | ALDH1A1HTTCDC7DBF4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298480-A | Plant growth regulators | ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) | 1994-03-29 | — | — | US | disclosed |
| WO-1993010103-A1 | HERBICIDAL SULFONYLURIA DERIVATIVES | ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) | 1993-05-27 | — | — | WO | disclosed |
| WO-1992006965-A1 | HERBICIDAL SULFONYLUREA DERIVATIVES | ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) | 1992-04-30 | — | — | WO | disclosed |
| EP-0457581-A1 | Herbicidal sulfonylurea derivatives | ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) | 1991-11-21 | — | — | EP | disclosed |