Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | ACHE | P22303 | 7/20 | 0.51 |
| ▸ | BCHE | P06276 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627983 | 0.85 | SMN1; SMN2 (1.00) | ALDH1A1L3MBTL1LMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10546975 | 0.84 | SMN1; SMN2 (0.97) | ALDH1A1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL31039479 | 0.82 | LMNA (0.62) | ALDH1A1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL12778520 | 0.82 | LMNA (0.61) | ALDH1A1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL9739727 | 0.81 | HTT (0.71) | ALDH1A1L3MBTL1LMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9736862 | 0.80 | HTT (0.70) | ALDH1A1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL9740908 | 0.78 | HTT (0.67) | ALDH1A1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL22911500 | 0.78 | SMN1; SMN2 (0.61) | ALDH1A1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL9741116 | 0.78 | ATM (0.59) | ALDH1A1L3MBTL1HTTSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL9741004 | 0.77 | HTT (0.65) | ALDH1A1L3MBTL1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110816-A | Urogenital disorders | INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES APPLIQUEES (I.R.C.E.B.A.) (FR) | 1992-05-05 | — | — | US | disclosed |