Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9741004 | 0.99 | HTT (0.65) | HTTSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9740898 | 0.83 | ALDH1A1 (0.54) | HTTSMN1; SMN2ALDH1A1LMNATP53 | |
| Hydrochloric Acid SCHEMBL9740988 | 0.82 | ATM (0.53) | HTTSMN1; SMN2ALDH1A1LMNATP53 | |
| SCHEMBL9627983 | 0.81 | SMN1; SMN2 (1.00) | HTTSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9739727 | 0.81 | HTT (0.71) | HTTSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9736862 | 0.80 | HTT (0.70) | HTTSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL10546975 | 0.80 | SMN1; SMN2 (0.97) | HTTSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9741129 | 0.78 | ALDH1A1 (0.75) | HTTSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9741672 | 0.74 | ATM (0.52) | HTTSMN1; SMN2ALDH1A1LMNATP53 | |
| SCHEMBL6583113 | 0.73 | ALDH1A1 (1.00) | SMN1; SMN2ALDH1A1LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110816-A | Urogenital disorders | INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES APPLIQUEES (I.R.C.E.B.A.) (FR) | 1992-05-05 | — | — | US | disclosed |