Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 4/20 | 0.60 |
| ▸ | DRD3 | P35462 | 4/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | DRD5 | P21918 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9736862 | 0.99 | HTT (0.70) | HTTSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9627983 | 0.83 | SMN1; SMN2 (1.00) | HTTSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL10546975 | 0.82 | SMN1; SMN2 (0.97) | HTTSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9741129 | 0.81 | ALDH1A1 (0.75) | HTTSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9740908 | 0.81 | HTT (0.67) | HTTSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9741004 | 0.80 | HTT (0.65) | HTTSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9739717 | 0.79 | ATM (0.62) | HTTSMN1; SMN2ALDH1A1LMNAHTR1A | |
| Hydrochloric Acid SCHEMBL9736847 | 0.78 | ATM (0.64) | HTTSMN1; SMN2ALDH1A1LMNAHTR1A | |
| Hydrochloric Acid SCHEMBL9736860 | 0.78 | ATM (0.64) | HTTSMN1; SMN2ALDH1A1LMNAHTR1A | |
| SCHEMBL8692475 | 0.74 | HTR1A (0.75) | HTR1ADRD3DRD2DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110816-A | Urogenital disorders | INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES APPLIQUEES (I.R.C.E.B.A.) (FR) | 1992-05-05 | — | — | US | disclosed |