Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.48 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 4/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742625 | 0.95 | ASIC3 (0.53) | ASIC3HRH3PLAUACACB | |
| SCHEMBL9742379 | 0.94 | TSHR (0.48) | ASIC3HRH3PLAUTSHRHSD17B10 | |
| SCHEMBL9742424 | 0.94 | ASIC3 (0.46) | ASIC3HRH3PLAUTSHRHSD17B10 | |
| SCHEMBL9743155 | 0.93 | TSHR (0.54) | ASIC3HRH3PLAUTSHRHSD17B10 | |
| SCHEMBL9743138 | 0.93 | TSHR (0.54) | ASIC3HRH3PLAUTSHRHSD17B10 | |
| SCHEMBL9742306 | 0.92 | ASIC3 (0.45) | ASIC3HRH3PLAUTSHRHSD17B10 | |
| SCHEMBL9743873 | 0.91 | HSD17B10 (0.56) | ASIC3HRH3TSHRHSD17B10 | |
| SCHEMBL9745311 | 0.91 | HSD17B10 (0.56) | ASIC3HRH3TSHRHSD17B10 | |
| SCHEMBL9742431 | 0.91 | HSD17B10 (0.56) | ASIC3HRH3TSHRHSD17B10 | |
| SCHEMBL9743477 | 0.90 | MCHR1 (0.48) | ASIC3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084204-A | Naphthylacetylenes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-01-28 | — | — | US | disclosed |