Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.42 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742359 | 0.95 | ASIC3 (0.49) | ASIC3HRH3FFAR1PLAUACACB | |
| SCHEMBL9741983 | 0.92 | ASIC3 (0.49) | ASIC3HRH3PLAUACACBTSHR | |
| SCHEMBL9743360 | 0.90 | TSHR (0.49) | ASIC3HRH3FFAR1TSHRHSD17B10 | |
| SCHEMBL9742424 | 0.89 | ASIC3 (0.46) | ASIC3HRH3PLAUACACBTSHR | |
| SCHEMBL9742625 | 0.87 | ASIC3 (0.53) | ASIC3HRH3FFAR1PLAUACACB | |
| SCHEMBL9742379 | 0.87 | TSHR (0.48) | ASIC3HRH3PLAUACACBTSHR | |
| SCHEMBL9743041 | 0.86 | ASIC3 (0.46) | ASIC3HRH3FFAR1PLAUACACB | |
| SCHEMBL9742429 | 0.85 | ACACB (0.46) | ASIC3HRH3ACACB | |
| SCHEMBL9743477 | 0.85 | MCHR1 (0.48) | ASIC3HRH3FFAR1 | |
| SCHEMBL9743155 | 0.85 | TSHR (0.54) | ASIC3HRH3PLAUTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084204-A | Naphthylacetylenes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-01-28 | — | — | US | disclosed |