Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742158 | 0.83 | HTR7 (0.59) | HTR7KCNH2DRD3HTR1ADRD4 | |
| SCHEMBL9745021 | 0.80 | HTR7 (0.64) | HTR7POLBDRD2DRD3HTR2C | |
| SCHEMBL9743262 | 0.80 | HTR7 (0.60) | HTR7HTR1A | |
| SCHEMBL9744074 | 0.80 | HTR7 (0.58) | HTR7DRD2DRD3HTR1AHTR2A | |
| SCHEMBL9743716 | 0.79 | DAO (0.52) | HTR7POLBDRD2DRD3HTR1A | |
| SCHEMBL16150983 | 0.77 | HTR7 (1.00) | HTR7 | |
| SCHEMBL9742212 | 0.76 | HTR7 (0.63) | HTR7DRD2DRD3HTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL16151313 | 0.76 | HTR7 (0.98) | HTR7 | |
| SCHEMBL16149726 | 0.76 | HTR7 (1.00) | HTR7 | |
| SCHEMBL13711971 | 0.76 | KCNH2 (0.71) | HTR7POLBKCNH2DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086055-A | Treating asthma, rhinitis, atopic dermatitis, chronic hives and conjunctivitis | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-02-04 | — | — | US | disclosed |