Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 7/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744074 | 0.88 | HTR7 (0.58) | HTR7ADRA1BADRA1DADRA1AHTR1A | |
| SCHEMBL9743716 | 0.87 | DAO (0.52) | HTR7ADRA1BADRA1DADRA1AHTR1A | |
| SCHEMBL9742212 | 0.86 | HTR7 (0.63) | HTR7ADRA1BADRA1DADRA1AHTR1A | |
| SCHEMBL9742158 | 0.84 | HTR7 (0.59) | HTR7HTR1A | |
| SCHEMBL9743826 | 0.81 | HTR7 (0.60) | HTR7 | |
| Maleic Acid SCHEMBL9741885 | 0.80 | HTR7 (0.51) | HTR7ADRA1BADRA1DADRA1AHTR1A | |
| Fumaric Acid SCHEMBL9741894 | 0.80 | HTR7 (0.51) | HTR7ADRA1BADRA1DADRA1AHTR1A | |
| SCHEMBL9742018 | 0.80 | HTR7 (0.62) | HTR7HTR1A | |
| SCHEMBL9742599 | 0.79 | HTR7 (0.61) | HTR7ADRA1BADRA1DADRA1AHTR1A | |
| SCHEMBL9743039 | 0.77 | HTR7 (0.57) | HTR7ADRA1AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086055-A | Treating asthma, rhinitis, atopic dermatitis, chronic hives and conjunctivitis | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-02-04 | — | — | US | disclosed |