Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 7/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743826 | 0.87 | HTR7 (0.60) | HTR7DRD4 | |
| SCHEMBL9743039 | 0.87 | HTR7 (0.57) | HTR7DRD4DRD3HTR1ASIGMAR1 | |
| SCHEMBL9742796 | 0.87 | HTR7 (0.49) | HTR7DRD4DRD3HTR1A | |
| SCHEMBL9743262 | 0.84 | HTR7 (0.60) | HTR7HTR1A | |
| SCHEMBL9744074 | 0.84 | HTR7 (0.58) | HTR7DRD3HTR1A | |
| SCHEMBL9743543 | 0.83 | HTR7 (0.57) | HTR7KCNH2DRD3HTR1ASIGMAR1 | |
| SCHEMBL9743716 | 0.83 | DAO (0.52) | HTR7DRD3HTR1ACYP2D6ALDH1A1 | |
| SCHEMBL9742018 | 0.83 | HTR7 (0.62) | HTR7KCNH2DRD4DRD3HTR1A | |
| Maleic Acid SCHEMBL9742763 | 0.82 | RAB9A (0.51) | HTR7KCNH2DRD4DRD3HTR1A | |
| Fumaric Acid SCHEMBL9742766 | 0.82 | RAB9A (0.51) | HTR7KCNH2DRD4DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086055-A | Treating asthma, rhinitis, atopic dermatitis, chronic hives and conjunctivitis | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-02-04 | — | — | US | disclosed |