Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742764 | 0.81 | SLC2A1 (0.49) | ALDH1A1SLC2A1ADRB2ADRB1SLC6A2 | |
| SCHEMBL9741406 | 0.81 | SLC2A1 (0.51) | ALDH1A1SLC2A1ADRB2ADRB1SLC6A2 | |
| SCHEMBL9741425 | 0.81 | SLC2A1 (0.49) | ALDH1A1SLC2A1ADRB2ADRB1SLC6A2 | |
| SCHEMBL10422236 | 0.77 | SLC2A1 (0.43) | ALDH1A1SLC2A1ADRB2ADRB1SLC6A2 | |
| SCHEMBL9741554 | 0.75 | SLC2A1 (0.49) | ALDH1A1SLC2A1ADRB2ADRB1SLC6A2 | |
| SCHEMBL9741718 | 0.73 | SLC2A1 (0.52) | SLC2A1ADRB2ADRB1SLC6A2SLC6A4 | |
| SCHEMBL9741980 | 0.73 | SLC2A1 (0.48) | SLC2A1ADRB2ADRB1SLC6A2SLC6A4 | |
| SCHEMBL9320952 | 0.72 | SLC2A1 (0.50) | ALDH1A1SLC2A1ADRB2ADRB1SLC6A2 | |
| SCHEMBL9764490 | 0.72 | ADRB2 (0.58) | ALDH1A1SLC2A1ADRB2ADRB1SLC6A2 | |
| SCHEMBL9764465 | 0.72 | ADRB2 (0.58) | ALDH1A1SLC2A1ADRB2ADRB1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149698-A | Pyrimidinyl alkyleneoxy bronchodilator agent | GLAXO GROUP LIMITED (GB) | 1992-09-22 | — | — | US | disclosed |
| US-4996218-A | Bronchodilator, antiulcer agent, cardiovascular disorders | GLAXO GROUP LIMITED (GB) | 1991-02-26 | — | — | US | disclosed |
| EP-0303464-A2 | Chloroaniline derivatives | GLAXO GROUP LIMITED (GB) | 1989-02-15 | — | — | EP | disclosed |