Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743187 | 1.00 | CYP19A1 (0.49) | CYP19A1MEN1MAPTRAB9AKMT2A | |
| SCHEMBL2218286 | 0.81 | MEN1 (0.49) | CYP19A1MEN1MAPTRAB9AKMT2A | |
| SCHEMBL9720425 | 0.81 | MEN1 (0.49) | CYP19A1MEN1MAPTRAB9AKMT2A | |
| SCHEMBL9743226 | 0.79 | ALOX5 (0.52) | MEN1MAPTRAB9AKMT2ALMNA | |
| SCHEMBL9743235 | 0.79 | ALOX5 (0.52) | MEN1MAPTRAB9AKMT2ALMNA | |
| SCHEMBL9743476 | 0.77 | HSD17B3 (0.42) | MEN1MAPTRAB9AKMT2ANPC1 | |
| SCHEMBL10930359 | 0.75 | GLA (0.63) | CYP19A1MEN1MAPTRAB9AKMT2A | |
| SCHEMBL10930364 | 0.75 | GLA (0.63) | CYP19A1MEN1MAPTRAB9AKMT2A | |
| SCHEMBL9743481 | 0.74 | HDAC1 (0.50) | MEN1MAPTRAB9AKMT2ANPC1 | |
| SCHEMBL9742099 | 0.74 | HDAC1 (0.50) | MEN1MAPTRAB9AKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096919-A | Pyrrolylphenyl-substituted hydroxamic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0378991-A1 | Certain pyrrolylphenyl-substituted hydroxamic acid derivatives | CIBA-GEIGY AG (CH) | 1990-07-25 | — | — | EP | disclosed |