Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743226 | 1.00 | ALOX5 (0.52) | ALOX5ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL6009904 | 0.84 | ALOX5 (0.63) | ALOX5ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL6009895 | 0.84 | ALOX5 (0.63) | ALOX5ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL9743187 | 0.79 | CYP19A1 (0.49) | ALDH1A1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL9743178 | 0.79 | CYP19A1 (0.49) | ALDH1A1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL9742084 | 0.77 | KDM4E (0.55) | ALOX5ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL9742089 | 0.77 | KDM4E (0.55) | ALOX5ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL9743831 | 0.76 | CA12 (0.60) | ALOX5ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL9743834 | 0.76 | CA12 (0.60) | ALOX5ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL9742787 | 0.74 | ALOX5 (0.55) | ALOX5ALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096919-A | Pyrrolylphenyl-substituted hydroxamic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1992-03-17 | — | — | US | claimed |
| EP-0378991-A1 | Certain pyrrolylphenyl-substituted hydroxamic acid derivatives | CIBA-GEIGY AG (CH) | 1990-07-25 | — | — | EP | claimed |
| US-5096919-A | Pyrrolylphenyl-substituted hydroxamic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0378991-A1 | Certain pyrrolylphenyl-substituted hydroxamic acid derivatives | CIBA-GEIGY AG (CH) | 1990-07-25 | — | — | EP | disclosed |