Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743328 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPK1MAPTPRKCA | |
| SCHEMBL9743603 | 0.90 | LMNA (0.46) | ALDH1A1LMNAMAPK1MAPTPRKCA | |
| SCHEMBL13221940 | 0.90 | MAPT (0.41) | ALDH1A1LMNAMAPK1MAPTPRKCA | |
| SCHEMBL9743208 | 0.90 | LMNA (0.50) | ALDH1A1LMNAMAPK1MAPTPRKCA | |
| SCHEMBL9744693 | 0.88 | LMNA (0.49) | ALDH1A1LMNAMAPK1MAPTPRKCA | |
| SCHEMBL9744819 | 0.88 | LMNA (0.57) | ALDH1A1LMNAMAPK1MAPTPRKCA | |
| SCHEMBL9743191 | 0.87 | NAAA (0.41) | ALDH1A1LMNAMAPK1MAPTPRKCA | |
| SCHEMBL9744414 | 0.87 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPK1MAPTPRKCA | |
| SCHEMBL9743058 | 0.87 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPK1MAPTPRKCA | |
| SCHEMBL9742392 | 0.87 | LMNA (0.59) | ALDH1A1LMNAMAPK1MAPTPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128252-A | Resolution of optically active esters, transesterification, lipase | CHISSO CORPORATION (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0384189-A2 | Optically active compound and a process for the production thereof | CHISSO CORPORATION (JP) | 1990-08-29 | — | — | EP | disclosed |