Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 13/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.39 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.39 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2647300 | 0.90 | GCGR (0.56) | GCGRALDH1A1L3MBTL1HTT | |
| SCHEMBL9152690 | 0.83 | GCGR (0.50) | GCGRALDH1A1L3MBTL1CACNB4CACNA1A | |
| SCHEMBL9743369 | 0.82 | GCGR (0.56) | GCGR | |
| SCHEMBL9269790 | 0.81 | GCGR (0.46) | GCGRALDH1A1L3MBTL1CACNB4CACNA1A | |
| SCHEMBL9745854 | 0.80 | GCGR (0.56) | GCGR | |
| SCHEMBL6962452 | 0.79 | GCGR (0.45) | GCGR | |
| SCHEMBL9744532 | 0.78 | GCGR (0.63) | GCGR | |
| SCHEMBL6958561 | 0.77 | GCGR (0.49) | GCGR | |
| SCHEMBL9743385 | 0.76 | TRPM8 (0.38) | GCGRALDH1A1L3MBTL1CACNB4CACNA1A | |
| SCHEMBL2662930 | 0.76 | GCGR (0.62) | GCGRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145857-A | HMG-COA REDUCTASE-INHIBITING SUBSTITUTED AMINO-PYRIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |