Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439501 | 0.87 | LOXL2 (0.41) | LOXL2HDAC6SMN1; SMN2NPSR1IDO1 | |
| SCHEMBL9439615 | 0.80 | SMN1; SMN2 (0.42) | LOXL2HDAC6SMN1; SMN2NPSR1IDO1 | |
| SCHEMBL6475090 | 0.80 | SMN1; SMN2 (0.42) | LOXL2HDAC6SMN1; SMN2NPSR1IDO1 | |
| SCHEMBL9744944 | 0.80 | LOXL2 (0.42) | LOXL2HDAC6SMN1; SMN2NPSR1IDO1 | |
| SCHEMBL9439614 | 0.79 | LOXL2 (0.41) | LOXL2HDAC6SMN1; SMN2NPSR1IDO1 | |
| SCHEMBL9743503 | 0.79 | TMEM97 (0.57) | LOXL2SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL11376480 | 0.79 | UBE2T (0.41) | LOXL2SMN1; SMN2IDO1GAANPC1 | |
| SCHEMBL9439557 | 0.78 | SMN1; SMN2 (0.40) | LOXL2HDAC6SMN1; SMN2NPSR1IDO1 | |
| SCHEMBL8127971 | 0.78 | ALOX5 (0.51) | LOXL2HDAC6IDO1ALOX5PPARA | |
| SCHEMBL9743920 | 0.77 | TMEM97 (0.44) | LOXL2GAAMEN1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294629-A | Benzothiazole and benzimidazole derivatives and antiulcer agent containing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 1994-03-15 | — | — | US | claimed |
| EP-0370436-A2 | Novel benzothiazole and benzimidazole derivatives and antiulcer agent containing the same | MEIJI SEIKA KAISHA LTD. (JP) | 1990-05-30 | — | — | EP | claimed |
| US-5294629-A | Benzothiazole and benzimidazole derivatives and antiulcer agent containing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0370436-A2 | Novel benzothiazole and benzimidazole derivatives and antiulcer agent containing the same | MEIJI SEIKA KAISHA LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |