Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 5/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATP4A | P20648 | 1/20 | 0.32 |
| ▸ | ATP4B | P51164 | 1/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439501 | 0.89 | LOXL2 (0.41) | LOXL2SMN1; SMN2NPSR1IDO1HDAC6 | |
| SCHEMBL6475090 | 0.88 | SMN1; SMN2 (0.42) | LOXL2SMN1; SMN2NPSR1IDO1HDAC6 | |
| SCHEMBL9439945 | 0.83 | HDAC6 (0.40) | LOXL2SMN1; SMN2NPSR1IDO1HDAC6 | |
| SCHEMBL9439614 | 0.81 | LOXL2 (0.41) | LOXL2SMN1; SMN2NPSR1IDO1HDAC6 | |
| SCHEMBL9439557 | 0.81 | SMN1; SMN2 (0.40) | LOXL2SMN1; SMN2NPSR1IDO1HDAC6 | |
| SCHEMBL9439734 | 0.80 | LOXL2 (0.47) | LOXL2SMN1; SMN2NPSR1IDO1HDAC6 | |
| SCHEMBL9439615 | 0.80 | SMN1; SMN2 (0.42) | LOXL2SMN1; SMN2NPSR1IDO1HDAC6 | |
| SCHEMBL9743401 | 0.78 | PTPN1 (0.42) | SMN1; SMN2GAAHTTPPARANPC1 | |
| SCHEMBL8127971 | 0.75 | ALOX5 (0.51) | LOXL2IDO1HDAC6PPARAALOX5 | |
| SCHEMBL9439576 | 0.74 | NPC1 (0.43) | SMN1; SMN2HDAC6GAAPPARAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171746-A | THIAZOLE AND IMIDAZOLE DERIVATIVES AND ANTIULCER COMPOSITION CONTAINING SAME | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0452076-A1 | Thiazole and imidazole derivatives and antiulcer composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-10-16 | — | — | EP | disclosed |