SCHEMBL9743535

SCHEMBL9743535

COC(=O)C(C)=CCCC[SiH](O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9743630 0.84 TBXAS1 (0.33)
SCHEMBL9745832 0.84
SCHEMBL18628094 0.74 CPB1 (0.40)
SCHEMBL2771421 0.72 EP300 (0.39) CYP2D6CYP2C19
SCHEMBL1584162 0.72 ALDH1A1 (0.34) CYP2D6CYP2C19
SCHEMBL689957 0.72 EP300 (0.39) CYP2D6CYP2C19
SCHEMBL3463543 0.71 PAOX (0.35) CYP2D6CYP2C19
SCHEMBL4919155 0.71 EP300 (0.47) CYP2C19
SCHEMBL2064032 0.71 PAOX (0.35) CYP2D6CYP2C19
SCHEMBL16583215 0.69 EP300 (0.50) CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5084537-A Contact lenses from organosilicon monomers that are oxygen permeable BAUSCH & LOMB, INCORPORATED (US) 1992-01-28 US disclosed
US-5002979-A Hyydrogenorganosilicon monomer, organosilicon, fluoroorgano monomer, a hydrophobic monomer and a crosslinking agent BAUSCH & LOMB INCORPORATED (US) 1991-03-26 US disclosed
EP-0215817-B1 CONTINUOUS-WEAR LENSES Bausch & Lomb Incorporated (US) 1991-03-13 EP disclosed
US-4829137-A Continuous-wear highly oxygen permeable contact lenses BAUSCH & LOMB INCORPORATED (US) 1989-05-09 US disclosed
EP-0209597-A1 EXTENDED-WEAR LENSES Bausch & Lomb Incorporated (US) 1987-01-28 EP disclosed
WO-1986004343-A1 EXTENDED-WEAR LENSES BAUSCH AND LOMB INCORPORATED (US) 1986-07-31 WO disclosed