Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | GCGR | P47871 | 7/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949830 | 0.81 | GCGR (0.45) | GCGR | |
| SCHEMBL8949790 | 0.81 | GCGR (0.40) | GCGR | |
| SCHEMBL8880943 | 0.69 | GCGR (0.45) | SCN9AGCGR | |
| SCHEMBL8949704 | 0.69 | NPC1 (0.43) | GCGRHMGCR | |
| SCHEMBL28320987 | 0.69 | GCGR (0.51) | GCGR | |
| SCHEMBL2663566 | 0.69 | GCGR (0.58) | GCGR | |
| SCHEMBL27506734 | 0.68 | GCGR (0.41) | GCGR | |
| SCHEMBL9870937 | 0.67 | GCGR (0.60) | SCN9AGCGRFPR2 | |
| SCHEMBL8949766 | 0.66 | GCGR (0.40) | GCGR | |
| SCHEMBL8876861 | 0.65 | GCGR (0.46) | GCGRHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145857-A | HMG-COA REDUCTASE-INHIBITING SUBSTITUTED AMINO-PYRIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |