Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 17/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949790 | 0.85 | GCGR (0.40) | GCGR | |
| SCHEMBL8949766 | 0.84 | GCGR (0.40) | GCGR | |
| SCHEMBL28320987 | 0.81 | GCGR (0.51) | GCGR | |
| SCHEMBL9744007 | 0.81 | SCN9A (0.35) | GCGR | |
| SCHEMBL2663566 | 0.81 | GCGR (0.58) | GCGR | |
| SCHEMBL27506734 | 0.79 | GCGR (0.41) | GCGR | |
| SCHEMBL8880943 | 0.78 | GCGR (0.45) | GCGR | |
| SCHEMBL8949911 | 0.78 | HMGCR (0.53) | GCGR | |
| SCHEMBL8877661 | 0.77 | GCGR (0.46) | GCGR | |
| SCHEMBL8876861 | 0.76 | GCGR (0.46) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502057-A | Polysubstituted pyridines useful for treating lipoproteinanaemia and arteriosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| US-5470982-A | Disubstituted pyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1995-11-28 | — | — | US | disclosed |
| US-5173495-A | 7-[(2,6-dialkyl-4-furyl or thienyl-pyridyl)]-3,5-di-(dihydroxy-6-enoates) useful for treating circulatory diseases | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-22 | — | — | US | disclosed |
| US-4968689-A | Certain 2,6-diisopropyl-4-(4-fluoro-phenyl)-3,5-bis-dimethyl-3',5'-dihydroxy-hept-6-enoate-pyridine derivatives useful for treating lipoproteinaemia and arteriosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |