Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.42 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744166 | 0.87 | L3MBTL1 (0.54) | KDM4EPTGS1L3MBTL1TDP1MAPT | |
| SCHEMBL9744184 | 0.87 | L3MBTL1 (0.54) | KDM4EPTGS1L3MBTL1TDP1MAPT | |
| SCHEMBL9744130 | 0.87 | KDM4E (0.56) | KDM4EPTGS1L3MBTL1TDP1MAPT | |
| SCHEMBL9744140 | 0.87 | KDM4E (0.56) | KDM4EPTGS1L3MBTL1TDP1MAPT | |
| SCHEMBL9743976 | 0.85 | NR1I2 (0.55) | KDM4EPTGS1L3MBTL1TDP1MAPT | |
| SCHEMBL9743985 | 0.85 | NR1I2 (0.55) | KDM4EPTGS1L3MBTL1TDP1MAPT | |
| SCHEMBL9548110 | 0.82 | DRD3 (0.49) | KDM4EPTGS1HPGDALDH1A1HSD17B10 | |
| SCHEMBL9745378 | 0.79 | KDM4E (0.43) | KDM4EPTGS1L3MBTL1TDP1MAPT | |
| SCHEMBL9745004 | 0.79 | NR1I2 (0.62) | PTGS1L3MBTL1TDP1MAPTNR1I2 | |
| SCHEMBL30229691 | 0.79 | NR1I2 (0.62) | PTGS1L3MBTL1TDP1MAPTNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147871-A | Anti-bacterial cephalosporin compounds | HOFFMANN LA-ROCHE, INC. (US) | 1992-09-15 | — | — | US | disclosed |