Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744130 | 1.00 | KDM4E (0.56) | KDM4EMAPTHPGDNR1I2TDP1 | |
| SCHEMBL9743976 | 0.89 | NR1I2 (0.55) | KDM4EMAPTHPGDNR1I2TDP1 | |
| SCHEMBL9743985 | 0.89 | NR1I2 (0.55) | KDM4EMAPTHPGDNR1I2TDP1 | |
| SCHEMBL9745731 | 0.89 | ALDH1A1 (0.57) | KDM4EMAPTHPGDALDH1A1HSD17B10 | |
| SCHEMBL9744166 | 0.88 | L3MBTL1 (0.54) | KDM4EMAPTHPGDNR1I2TDP1 | |
| SCHEMBL9744184 | 0.88 | L3MBTL1 (0.54) | KDM4EMAPTHPGDNR1I2TDP1 | |
| SCHEMBL9744018 | 0.87 | KDM4E (0.50) | KDM4EMAPTHPGDNR1I2TDP1 | |
| SCHEMBL9744180 | 0.85 | DRD3 (0.55) | KDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL9020827 | 0.84 | KDM4E (0.54) | KDM4EMAPTHPGDTDP1ALDH1A1 | |
| SCHEMBL9745004 | 0.82 | NR1I2 (0.62) | MAPTNR1I2TDP1SLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147871-A | Anti-bacterial cephalosporin compounds | HOFFMANN LA-ROCHE, INC. (US) | 1992-09-15 | — | — | US | disclosed |