Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 3/20 | 0.41 |
| ▸ | SLC22A11 | Q9NSA0 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | APEX1 | P27695 | 2/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9844206 | 0.88 | KDM4E (0.42) | KDM4ENR1I2MAPTSLC22A6SLC22A8 | |
| SCHEMBL30229691 | 0.83 | NR1I2 (0.62) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL9745004 | 0.83 | NR1I2 (0.62) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| Hydrochloric Acid SCHEMBL9844164 | 0.83 | NR1I2 (0.62) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL9744140 | 0.82 | KDM4E (0.56) | KDM4ENR1I2MAPTSLC22A6SLC22A8 | |
| SCHEMBL9744130 | 0.82 | KDM4E (0.56) | KDM4ENR1I2MAPTSLC22A6SLC22A8 | |
| SCHEMBL9744042 | 0.82 | NR1I2 (0.54) | KDM4ENR1I2MAPTSLC22A6SLC22A8 | |
| Trifluoroacetic Acid SCHEMBL9878470 | 0.81 | NR1I2 (0.59) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL13576357 | 0.80 | NR1I2 (0.60) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL9744018 | 0.79 | KDM4E (0.50) | KDM4ENR1I2MAPTSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147871-A | Anti-bacterial cephalosporin compounds | HOFFMANN LA-ROCHE, INC. (US) | 1992-09-15 | — | — | US | disclosed |