Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 7/20 | 0.47 |
| ▸ | TUBB | P07437 | 7/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10588429 | 0.87 | KDM4E (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Trifluoroacetic Acid SCHEMBL9844206 | 0.86 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9744163 | 0.83 | DRD3 (0.44) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9744694 | 0.80 | KDM4E (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9548111 | 0.80 | KDM4E (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10378457 | 0.79 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9745378 | 0.79 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10914907 | 0.76 | MAPT (0.64) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9745004 | 0.73 | NR1I2 (0.62) | ALDH1A1HSD17B10ALBHRH3POLB | |
| SCHEMBL30229691 | 0.73 | NR1I2 (0.62) | ALDH1A1HSD17B10ALBHRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147871-A | Anti-bacterial cephalosporin compounds | HOFFMANN LA-ROCHE, INC. (US) | 1992-09-15 | — | — | US | disclosed |