Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 3/20 | 0.40 |
| ▸ | SLC22A11 | Q9NSA0 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | PGR | P06401 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 3/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745378 | 0.88 | KDM4E (0.43) | KDM4ENR1I2MAPTSLC22A6SLC22A8 | |
| SCHEMBL9744163 | 0.87 | DRD3 (0.44) | KDM4ENR1I2MAPTSLC22A6SLC22A8 | |
| SCHEMBL9744095 | 0.86 | TUBB4A (0.47) | KDM4ENR1I2MAPTSLC22A6SLC22A8 | |
| Trifluoroacetic Acid SCHEMBL9878470 | 0.85 | NR1I2 (0.59) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL9744042 | 0.83 | NR1I2 (0.54) | KDM4ENR1I2MAPTSLC22A6SLC22A8 | |
| SCHEMBL30229691 | 0.82 | NR1I2 (0.62) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL9745004 | 0.82 | NR1I2 (0.62) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| Hydrochloric Acid SCHEMBL9844164 | 0.82 | NR1I2 (0.62) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL9744140 | 0.81 | KDM4E (0.56) | KDM4ENR1I2MAPTSLC22A6SLC22A8 | |
| SCHEMBL9744130 | 0.81 | KDM4E (0.56) | KDM4ENR1I2MAPTSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066800-A | For coupling cephalosporins to quinolines(or derivatives) | HOFFMANN-LA ROCHE INC. (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0453952-A2 | A process for synthesizing cephalosporin compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1991-10-30 | — | — | EP | disclosed |