Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10378457 | 0.87 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10NR1I2 | |
| Trifluoroacetic Acid SCHEMBL9844206 | 0.87 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10NR1I2 | |
| SCHEMBL9744180 | 0.83 | DRD3 (0.55) | DRD3KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL9744109 | 0.83 | NR1I2 (0.53) | ALDH1A1KMT2AHSD17B10NR1I2ALB | |
| SCHEMBL9744095 | 0.83 | TUBB4A (0.47) | KDM4EALDH1A1HPGDHSD17B10NR1I2 | |
| SCHEMBL9551564 | 0.81 | NR1I2 (0.62) | ALDH1A1KMT2AHSD17B10NR1I2ALB | |
| SCHEMBL9551553 | 0.81 | NR1I2 (0.62) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL9744151 | 0.80 | NR1I2 (0.41) | ALDH1A1HPGDHSD17B10NR1I2ALB | |
| SCHEMBL9744011 | 0.80 | NR1I2 (0.54) | ALDH1A1KMT2AHSD17B10NR1I2ALB | |
| SCHEMBL9745731 | 0.80 | ALDH1A1 (0.57) | DRD3KDM4EALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147871-A | Anti-bacterial cephalosporin compounds | HOFFMANN LA-ROCHE, INC. (US) | 1992-09-15 | — | — | US | disclosed |