Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.80 |
| ▸ | HPGD | P15428 | 1/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.80 |
| ▸ | HTT | P42858 | 1/20 | 0.80 |
| ▸ | RAB9A | P51151 | 1/20 | 0.80 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | IAPP | P10997 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744288 | 0.89 | HTT (1.00) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27930400 | 0.89 | NPC1 (0.91) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL9745513 | 0.87 | HTT (0.88) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL9745054 | 0.86 | NPC1 (0.59) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL20477532 | 0.85 | HTT (0.92) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL18782422 | 0.85 | HTT (0.92) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL9743684 | 0.83 | NPC1 (0.88) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL9745357 | 0.83 | NPC1 (0.80) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27693672 | 0.83 | HTT (0.88) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL9743295 | 0.82 | HTT (0.72) | NPC1HPGDMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0227487-A2 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |