Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 7/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744919 | 0.92 | HTT (0.40) | CHRM5SMN1; SMN2NPSR1LMNAKMT2A | |
| SCHEMBL9742194 | 0.90 | SMN1; SMN2 (0.43) | CHRM5SMN1; SMN2NPSR1LMNAKMT2A | |
| SCHEMBL9742447 | 0.88 | ADAM17 (0.40) | CHRM5SMN1; SMN2HTTMDM2HTR2A | |
| SCHEMBL9743436 | 0.87 | GRIN1 (0.39) | CHRM5SMN1; SMN2NPSR1LMNAKMT2A | |
| SCHEMBL9742428 | 0.87 | LMNA (0.37) | CHRM5SMN1; SMN2NPSR1LMNAKMT2A | |
| SCHEMBL9742083 | 0.87 | CHRM5 (0.43) | CHRM5NPSR1LMNAKMT2AHTT | |
| SCHEMBL9744554 | 0.84 | CHRM5 (0.43) | CHRM5MDM2TP53 | |
| SCHEMBL9742586 | 0.84 | HTT (0.38) | CHRM5SMN1; SMN2NPSR1LMNAKMT2A | |
| SCHEMBL9743467 | 0.82 | PARP1 (0.43) | CHRM5LMNAKMT2APARP1MAPT | |
| SCHEMBL9741939 | 0.82 | SMN1; SMN2 (0.43) | CHRM5SMN1; SMN2NPSR1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016529-A1 | NOVEL ISOINDOLE DERIVATIVES AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-01 | — | — | WO | disclosed |