Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744150 | 0.92 | CHRM5 (0.40) | HTTSMN1; SMN2LMNANPSR1KMT2A | |
| SCHEMBL9742447 | 0.92 | ADAM17 (0.40) | HTTSMN1; SMN2CHRM5HTR2AHTR2C | |
| SCHEMBL9743436 | 0.92 | GRIN1 (0.39) | HTTSMN1; SMN2LMNANPSR1MEN1 | |
| SCHEMBL9742083 | 0.89 | CHRM5 (0.43) | HTTLMNANPSR1MEN1KMT2A | |
| SCHEMBL9744554 | 0.89 | CHRM5 (0.43) | CHRM5HSD11B1MDM2 | |
| SCHEMBL9741939 | 0.89 | SMN1; SMN2 (0.43) | HTTSMN1; SMN2LMNANPSR1MEN1 | |
| SCHEMBL9742586 | 0.88 | HTT (0.38) | HTTSMN1; SMN2LMNANPSR1MEN1 | |
| SCHEMBL9739008 | 0.86 | SMN1; SMN2 (0.55) | HTTSMN1; SMN2LMNANPSR1MEN1 | |
| SCHEMBL9742428 | 0.84 | LMNA (0.37) | HTTSMN1; SMN2LMNANPSR1MEN1 | |
| SCHEMBL9743342 | 0.84 | PSEN1 (0.40) | HTTSMN1; SMN2LMNANPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016529-A1 | NOVEL ISOINDOLE DERIVATIVES AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-01 | — | — | WO | disclosed |