Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744143 | 0.98 | HSD17B10 (0.45) | HSD17B10KDM4EALDH1A1DRD3MEN1 | |
| Potassium Ion SCHEMBL9744147 | 0.90 | ALDH1A1 (0.42) | HSD17B10KDM4EALDH1A1DRD3MEN1 | |
| SCHEMBL4766471 | 0.81 | ALDH1A1 (0.60) | HSD17B10KDM4EALDH1A1DRD3MEN1 | |
| SCHEMBL9743791 | 0.80 | DRD3 (0.45) | HSD17B10KDM4EALDH1A1DRD3MEN1 | |
| SCHEMBL9743778 | 0.80 | DRD3 (0.45) | HSD17B10KDM4EALDH1A1DRD3MEN1 | |
| SCHEMBL4768364 | 0.77 | HSD17B10 (0.75) | HSD17B10KDM4EALDH1A1DRD3MEN1 | |
| SCHEMBL30306133 | 0.77 | HSD17B10 (0.75) | HSD17B10KDM4EALDH1A1DRD3MEN1 | |
| SCHEMBL21937028 | 0.73 | MAPT (0.51) | HSD17B10KDM4EALDH1A1LMNAHTT | |
| SCHEMBL710108 | 0.72 | ALDH1A1 (0.51) | HSD17B10KDM4EALDH1A1LMNAHTT | |
| SCHEMBL20521398 | 0.72 | SMN1; SMN2 (0.49) | HSD17B10KDM4EALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147871-A | Anti-bacterial cephalosporin compounds | HOFFMANN LA-ROCHE, INC. (US) | 1992-09-15 | — | — | US | disclosed |