Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | USP7 | Q93009 | 4/20 | 0.41 |
| ▸ | USP47 | Q96K76 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11806953 | 0.91 | CA12 (0.56) | CA12CA9VCAM1SLC9A1MAPT | |
| SCHEMBL13483711 | 0.86 | TSHR (0.44) | CA12CA9MAPTLMNAGPR35 | |
| SCHEMBL7744981 | 0.86 | CA12 (0.46) | CA12CA9VCAM1SLC9A1MAPT | |
| SCHEMBL10740278 | 0.83 | CA12 (0.44) | CA12CA9VCAM1SLC9A1MAPT | |
| SCHEMBL10741897 | 0.83 | HCAR3 (0.44) | CA12CA9VCAM1MAPTLMNA | |
| SCHEMBL3902768 | 0.82 | DTYMK (0.51) | VCAM1LMNAGPR35TSHRMAPK1 | |
| SCHEMBL8138894 | 0.82 | VCAM1 (0.46) | VCAM1SLC9A1LMNAGPR35TSHR | |
| SCHEMBL26353448 | 0.81 | CA12 (0.55) | CA12CA9VCAM1SLC9A1MAPT | |
| SCHEMBL6209266 | 0.81 | SLC9A1 (0.39) | CA12CA9VCAM1SLC9A1MAPT | |
| SCHEMBL6209263 | 0.81 | SLC9A1 (0.39) | CA12CA9VCAM1SLC9A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138088-A | Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the preparation thereof | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1992-08-11 | — | — | US | disclosed |
| US-4656267-A | RENAL VASODILATORS, CARDIOVASCULAR AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-04-07 | — | — | US | disclosed |
| US-4555571-A | Substituted 2(1H)-quinazolinone-1-alkanoic acids and esters | ORTHO PHARMACEUTICAL CORPORATION (US) | 1985-11-26 | — | — | US | disclosed |
| EP-0138491-A2 | Substituted 2(1H)-quinazolinone-1-alkanoic acids and esters | ORTHO PHARMACEUTICAL CORPORATION (US) | 1985-04-24 | — | — | EP | disclosed |
| US-4379929-A | BACTERIOSTATS | ELI LILLY AND COMPANY (US) | 1983-04-12 | — | — | US | disclosed |