SCHEMBL974418

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL974382	0.92	GRM5 (0.42)	GRM5PCSK9EPHX2CDK8RAF1
	SCHEMBL972309	0.90	NTMT1 (0.36)	GRM5
	SCHEMBL973350	0.90	SMPD3 (0.38)	EPHX2TRPV1CA12CA1CA2
	SCHEMBL974369	0.89	CCR4 (0.36)	GRM5CDK8MEN1KMT2ABTK
	SCHEMBL971724	0.88	CNR2 (0.40)	GRM5CDK8BTK
	SCHEMBL974388	0.88	DRD2 (0.43)	MEN1KMT2AALDH1A1BTK
	SCHEMBL971187	0.87	MTNR1A (0.42)	GRM5CDK8KMT2AALDH1A1
	SCHEMBL4703399	0.86	PCSK9 (0.44)	GRM5PCSK9EPHX2RAF1BRAF
	SCHEMBL973624	0.85	CNR2 (0.38)	CDK8TRPV1CA12CA1CA2
	SCHEMBL973618	0.85	PCSK9 (0.43)	GRM5PCSK9EPHX2CDK8MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.