Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3905172 | 0.84 | ALDH1A1 (0.53) | SMN1; SMN2LMNATP53MAPK1ALDH1A1 | |
| SCHEMBL29542545 | 0.84 | ALDH1A1 (0.53) | SMN1; SMN2LMNATP53MAPK1ALDH1A1 | |
| SCHEMBL9744198 | 0.82 | MAPK1 (0.41) | SMN1; SMN2LMNATP53MAPK1ALDH1A1 | |
| SCHEMBL21142245 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNATP53MAPK1ALDH1A1 | |
| Fluoride SCHEMBL28748040 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNATP53MAPK1ALDH1A1 | |
| SCHEMBL10621054 | 0.79 | LMNA (0.50) | SMN1; SMN2LMNATP53MAPK1ALDH1A1 | |
| SCHEMBL12307044 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNATP53MAPK1ALDH1A1 | |
| SCHEMBL29973281 | 0.77 | MEN1 (0.51) | SMN1; SMN2LMNATP53MAPK1ALDH1A1 | |
| SCHEMBL7948831 | 0.77 | MEN1 (0.51) | SMN1; SMN2LMNATP53MAPK1ALDH1A1 | |
| SCHEMBL21791652 | 0.76 | ALDH1A1 (0.47) | SMN1; SMN2LMNATP53MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155195-A | Sidechain copolymers exhibiting nonlinear optical response | HOECHST CELANESE CORP. (US) | 1992-10-13 | — | — | US | disclosed |