SCHEMBL9744204

SCHEMBL9744204

CCOC(=O)CNc1cc(F)ccc1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CLCN2 P51788 1/20 0.45
LMNA P02545 2/20 0.43
POLB P06746 2/20 0.43
KMT2A Q03164 3/20 0.41
MAPT P10636 3/20 0.41
MEN1 O00255 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TSHR P16473 1/20 0.39
PPID Q08752 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8432960 0.83 MEN1 (0.56) POLBKMT2AMEN1NPSR1ALDH1A1
SCHEMBL14523952 0.82 LMNA (0.39) LMNAPOLBKMT2AMAPTMEN1
SCHEMBL4017286 0.81 MAPT (0.56) LMNAPOLBKMT2AMAPTMEN1
SCHEMBL9573784 0.81 LMNA (0.52) LMNAPOLBKMT2AMAPTMEN1
SCHEMBL9744548 0.81 CLCN2 (0.46) CLCN2KMT2AMAPTMEN1ALDH1A1
SCHEMBL13921285 0.81 CLCN2 (0.49) CLCN2KMT2AMAPTMEN1ALDH1A1
SCHEMBL31518574 0.80 KDM4E (0.58) CLCN2LMNAPOLBKMT2AMEN1
SCHEMBL8540162 0.78 GLA (0.49) LMNAPOLBKMT2AMAPTMEN1
SCHEMBL7802433 0.77 LMNA (0.61) LMNAPOLBKMT2AMAPTNPSR1
SCHEMBL8196433 0.75 LMNA (0.72) LMNAPOLBKMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5093364-A 5-FLUOROANTHRANILIC FUNGICIDES SCHERING AGROCHEMICALS LIMITED (GB) 1992-03-03 US disclosed
EP-0360417-A2 Derivatives of 4-fluoroanthranilic acid and their use as fungicides SCHERING AGROCHEMICALS LIMITED (GB) 1990-03-28 EP disclosed