Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 13/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | CDK9 | P50750 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435289 | 0.91 | GRIK1 (0.80) | GRIK1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL31078982 | 0.83 | RAB9A (0.69) | GRIK1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL848085 | 0.82 | AKR1C3 (0.60) | GRIK1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL5595292 | 0.82 | GRIK1 (0.71) | GRIK1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL3957527 | 0.81 | GRIK1 (1.00) | GRIK1 | |
| SCHEMBL17609477 | 0.81 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL3962742 | 0.81 | GRIK1 (1.00) | GRIK1 | |
| SCHEMBL6431737 | 0.80 | GRIK1 (1.00) | GRIK1NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL6677249 | 0.80 | SMN1; SMN2 (0.66) | GRIK1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL1462332 | 0.80 | KDM4E (0.71) | GRIK1NPC1RAB9ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093364-A | 5-FLUOROANTHRANILIC FUNGICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-03-03 | — | — | US | disclosed |
| EP-0360417-A2 | Derivatives of 4-fluoroanthranilic acid and their use as fungicides | SCHERING AGROCHEMICALS LIMITED (GB) | 1990-03-28 | — | — | EP | disclosed |