Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.46 |
| ▸ | HNF4A | P41235 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.41 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.41 |
| ▸ | PPM1B | O75688 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5834234 | 0.82 | MYC (0.47) | KDM4EKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7745596 | 0.80 | GABRP (0.42) | KDM4EKMT2ACYP1A2 | |
| SCHEMBL9743092 | 0.79 | POLB (0.46) | KDM4EGFERSMN1; SMN2 | |
| SCHEMBL9743151 | 0.77 | APEX1 (0.45) | KDM4ECYP1A2ACLY | |
| SCHEMBL5026623 | 0.76 | MCL1 (0.44) | HNF4AKDM4EMCL1CYP1A2 | |
| SCHEMBL9742325 | 0.76 | GABRP (0.39) | KDM4EKMT2ACYP1A2LCK | |
| SCHEMBL106081 | 0.74 | ALDH1A1 (0.56) | KDM4ESMN1; SMN2 | |
| SCHEMBL28418946 | 0.73 | CYP3A4 (0.41) | KDM4EKMT2ACYP1A2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9411948 | 0.72 | ALDH1A1 (0.54) | KDM4ESMN1; SMN2 | |
| SCHEMBL30690398 | 0.72 | KMT2A (0.62) | ACMSDHNF4ARXFP1KDM4EGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082959-A | Oxidation of alkyl groups substituted on a trialkylsilyl-substituted aromatic ring using oxygen gas and a cobalt and/or manganese compound and a bromide as catalyts | AMOCO CORPORATION (US) | 1992-01-21 | — | — | US | disclosed |