Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744286 | 0.77 | ACMSD (0.46) | KDM4EACLYCYP1A2 | |
| SCHEMBL1397921 | 0.77 | APEX1 (0.67) | APEX1POLBCTDSP1L3MBTL1KDM4E | |
| SCHEMBL29364883 | 0.77 | APEX1 (0.67) | APEX1POLBCTDSP1L3MBTL1KDM4E | |
| SCHEMBL29394064 | 0.77 | APEX1 (0.67) | APEX1POLBCTDSP1L3MBTL1KDM4E | |
| SCHEMBL65212 | 0.77 | APEX1 (0.67) | APEX1POLBCTDSP1L3MBTL1KDM4E | |
| SCHEMBL2807317 | 0.76 | APEX1 (0.53) | APEX1POLBCTDSP1L3MBTL1KDM4E | |
| SCHEMBL9743140 | 0.76 | ALDH1A1 (0.32) | KDM4ELMNAALDH1A1GAAMAPT | |
| SCHEMBL5834234 | 0.76 | MYC (0.47) | POLBL3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL268999 | 0.75 | APEX1 (0.65) | APEX1POLBCTDSP1L3MBTL1KDM4E | |
| SCHEMBL8999902 | 0.75 | APEX1 (0.70) | APEX1POLBCTDSP1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082959-A | Oxidation of alkyl groups substituted on a trialkylsilyl-substituted aromatic ring using oxygen gas and a cobalt and/or manganese compound and a bromide as catalyts | AMOCO CORPORATION (US) | 1992-01-21 | — | — | US | disclosed |